
1. Male vs Female Reproductive System
| Feature | Male reproductive system | Female reproductive system |
|---|---|---|
| Primary sex organ | Pair of testes in the scrotum | Pair of ovaries in the pelvic cavity |
| Gamete produced | Sperm / spermatozoon | Ovum / secondary oocyte |
| Main ducts | Rete testis → vasa efferentia → epididymis → vas deferens → ejaculatory duct → urethra | Oviducts, uterus, cervix and vagina |
| Accessory glands / organs | Seminal vesicles, prostate and bulbourethral glands add seminal plasma | Uterus supports implantation and development; mammary glands nourish the newborn |
| Key hormones | Testosterone and inhibin from testes | Oestrogens, progesterone, inhibin and relaxin from ovaries / placenta |
2. Spermatogenesis vs Oogenesis
| Point | Spermatogenesis | Oogenesis |
|---|---|---|
| Site | Seminiferous tubules of testes | Ovarian follicles |
| Begins | At puberty | During embryonic development |
| Stem cells | Spermatogonia (2n) | Oogonia (2n) |
| Meiosis I product | Two equal haploid secondary spermatocytes | Large secondary oocyte + small first polar body |
| Meiosis II product | Four spermatids that differentiate into spermatozoa | Completed only after sperm entry; ovum + second polar body |
| Cytokinesis | Equal | Unequal; cytoplasm is conserved in the ovum |
| Output per primary cell | Four functional sperm | One functional ovum |
High-yieldSpermiogenesis converts spermatids into spermatozoa; spermiation releases spermatozoa from Sertoli cells into the lumen.
3. Sperm vs Ovum
| Feature | Sperm | Ovum / secondary oocyte |
|---|---|---|
| Size and motility | Small, motile and flagellated | Large, non-motile, rich in cytoplasm |
| Main regions | Head, neck, middle piece and tail | Plasma membrane, zona pellucida and corona radiata |
| Special structures | Acrosome has enzymes for fertilisation; middle piece has mitochondria | Cortical reaction after sperm entry blocks polyspermy |
| Chromosomes | Haploid; carries X or Y chromosome | Haploid; always carries X chromosome |
| Contribution to zygote | Paternal genome and centriole | Maternal genome, cytoplasm and organelles |
4. Ovarian Cycle vs Menstrual Cycle
| Phase | Ovarian events | Uterine / menstrual events | Hormonal cue |
|---|---|---|---|
| Menstrual phase (day 1-5) | New follicles begin growth | Endometrium is shed if fertilisation did not occur | Fall in progesterone and oestrogen |
| Follicular / proliferative phase (day 6-13) | Follicles develop; one becomes dominant Graafian follicle | Endometrium regenerates and proliferates | FSH stimulates follicles; oestrogen rises |
| Ovulation (about day 14) | Secondary oocyte is released from Graafian follicle | Endometrium remains receptive | Mid-cycle LH surge |
| Luteal / secretory phase (day 15-28) | Ruptured follicle becomes corpus luteum | Endometrium becomes vascular and secretory | Progesterone predominates |
5. Fertilisation, Implantation and Parturition
| Event | Site / timing | Key outcome |
|---|---|---|
| Fertilisation | Ampullary-isthmic junction of oviduct | Haploid sperm and secondary oocyte fuse to form diploid zygote |
| Cleavage | During movement through oviduct | Zygote → 2, 4, 8, 16 blastomeres; 8-16 cell stage is morula |
| Blastocyst formation | Before uterine implantation | Outer trophoblast and inner cell mass differentiate |
| Implantation | Endometrium of uterus | Blastocyst embeds in uterine wall; pregnancy begins |
| Placenta | Maternal endometrium + embryonic chorionic villi | Exchange of nutrients, gases and wastes; endocrine support |
| Parturition | End of gestation | Foetal ejection reflex and oxytocin cause strong uterine contractions |
Fertilisation→Morula→Blastocyst→Implantation→Placenta & foetus
6. Major Hormones in Human Reproduction
| Hormone | Main source | Core action |
|---|---|---|
| GnRH | Hypothalamus | Stimulates anterior pituitary release of FSH and LH |
| FSH | Anterior pituitary | Acts on Sertoli cells; stimulates follicular development in ovary |
| LH | Anterior pituitary | Acts on Leydig cells; triggers ovulation and corpus luteum formation |
| Testosterone | Leydig cells | Supports spermatogenesis and male secondary sexual characters |
| Oestrogens | Growing follicles / ovary | Female secondary sexual characters and endometrial proliferation |
| Progesterone | Corpus luteum; placenta | Maintains endometrium and supports pregnancy |
| hCG | Placenta | Maintains corpus luteum early in pregnancy; basis of pregnancy tests |
| Prolactin / oxytocin | Anterior / posterior pituitary | Milk synthesis / milk ejection and uterine contraction |
7. Identical vs Fraternal Twins, and Lactation Terms
| Term | Origin / meaning | Key point |
|---|---|---|
| Identical twins | One zygote divides during early embryonic development | Genetically identical and usually same sex |
| Fraternal twins | Two ova are fertilised by two different sperm | Genetically as similar as ordinary siblings; may be different sexes |
| Lactogenesis | Milk production after parturition | Stimulated mainly by prolactin |
| Milk ejection | Release of milk from mammary glands | Infant suckling triggers oxytocin release |
| Colostrum | First milk after childbirth | Rich in antibodies, especially IgA, and important for newborn immunity |