1. CNS vs PNS; Afferent vs Efferent Fibres
| Feature | CNS | PNS |
|---|---|---|
| Components | Brain and spinal cord | All nerves associated with CNS |
| Primary role | Information processing and control | Links CNS with body tissues and organs |
| Fibre | Direction of impulse | Role |
|---|---|---|
| Afferent | Tissues / organs -> CNS | Brings sensory input to CNS |
| Efferent | CNS -> peripheral tissues / organs | Carries regulatory output |
2. Somatic vs Autonomic vs Visceral Nervous System
| Division | Target / arrangement | Function |
|---|---|---|
| Somatic neural system | Skeletal muscles | Relays CNS impulses to skeletal muscles |
| Autonomic neural system | Involuntary organs and smooth muscles; includes sympathetic and parasympathetic divisions | Transmits CNS impulses to involuntary effectors |
| Visceral nervous system | Complex PNS network of nerves, fibres, ganglia and plexuses between CNS and viscera | Conducts impulses in both directions between CNS and viscera |
3. Dendrites vs Axon; Neuron Types
| Feature | Dendrites | Axon |
|---|---|---|
| Structure | Short and repeatedly branched projections with Nissl’s granules | Usually single long fibre; distal end branches into synaptic knobs |
| Impulse direction | Towards cell body | Away from cell body to synapse or neuromuscular junction |
| Terminal function | Receives / conducts input to soma | Synaptic vesicles in knob contain neurotransmitters |
| Neuron type | Processes | Example |
|---|---|---|
| Multipolar | One axon, two or more dendrites | Cerebral cortex |
| Bipolar | One axon, one dendrite | Retina |
| Unipolar | Cell body with one axon only | Usually embryonic stage |
4. Myelinated vs Non-myelinated Fibres
| Feature | Myelinated nerve fibre | Non-myelinated nerve fibre |
|---|---|---|
| Schwann-cell relation | Schwann cells form myelin sheath around axon | Schwann cell encloses axon but does not form myelin sheath |
| Nodes of Ranvier | Present as gaps between adjacent myelin sheaths | Not present |
| Occurrence | Spinal and cranial nerves | Common in autonomic and somatic neural systems |
5. Resting Potential vs Action Potential
| Feature | Resting potential / polarised state | Action potential / depolarised state |
|---|---|---|
| Membrane permeability | More permeable to K+, nearly impermeable to Na+ and negative proteins | Stimulus briefly makes membrane freely permeable to Na+ |
| Ion distribution | Inside: high K+, negative proteins, low Na+; outside: high Na+, low K+ | Rapid Na+ influx at stimulus site |
| Charge pattern | Outer surface positive, inner surface negative | Polarity reverses: outer becomes negative, inner positive |
| Maintenance / recovery | Na+-K+ pump sends 3 Na+ out for 2 K+ in | Subsequent K+ permeability rise permits K+ efflux and repolarisation |
6. Electrical vs Chemical Synapse
| Feature | Electrical synapse | Chemical synapse |
|---|---|---|
| Membrane relation | Pre- and post-synaptic membranes are very close | Fluid-filled synaptic cleft separates membranes |
| Transmission | Electrical current passes directly between neurons | Action potential triggers vesicle fusion and neurotransmitter release; transmitter binds specific post-synaptic receptors |
| Speed / occurrence | Faster; rare in human neural system | Slower than electrical synapse; common mechanism |
| Result | Like conduction along one axon | Ion channels open and new excitatory or inhibitory potential is produced |
7. Forebrain Structures
| Structure | Key structure | Major function |
|---|---|---|
| Cerebrum | Largest part; two hemispheres linked by corpus callosum. Cortex is grey matter; inner myelinated tracts are white matter. | Motor, sensory and association functions; memory and communication. |
| Thalamus | Wrapped by cerebrum | Major coordinating centre for sensory and motor signalling. |
| Hypothalamus | At base of thalamus; contains neurosecretory cells | Temperature, eating, drinking and hypothalamic hormones. |
| Limbic system | Inner cerebral hemispheres plus deep structures such as amygdala and hippocampus | Sexual behaviour, emotion, motivation, excitement, pleasure, rage and fear. |
8. Midbrain vs Hindbrain Components
| Region | Location / structure | Function |
|---|---|---|
| Midbrain | Between thalamus/hypothalamus and pons; cerebral aqueduct passes through it; dorsal corpora quadrigemina | Integrates visual, tactile and auditory inputs |
| Pons | Part of hindbrain and brain stem | Fibre tracts interconnect brain regions |
| Cerebellum | Highly convoluted surface | Integrates information for balance and coordination |
| Medulla oblongata | Connects to spinal cord; part of brain stem | Controls respiration, cardiovascular reflexes and gastric secretions |
Brain stem Midbrain, pons and medulla oblongata together connect brain and spinal cord. The brain is covered by dura mater, arachnoid and pia mater beneath the skull.