1. Movement vs Locomotion; Types of Movement
| Term / type | Definition or mechanism | Examples |
|---|---|---|
| Movement | Change in position of whole body or body part | Limbs, jaws, eyelids, tongue, cilia and tentacles |
| Locomotion | Voluntary movement resulting in change of place | Walking, running, climbing, flying and swimming |
| Amoeboid movement | Pseudopodia formed by protoplasmic streaming; microfilaments participate | Macrophages and leucocytes |
| Ciliary movement | Coordinated ciliary beating in internal tubular organs | Dust removal in trachea; passage of ova |
| Muscular movement | Muscle contraction moves body parts | Limbs, jaws and tongue |
2. Skeletal vs Visceral vs Cardiac Muscle
| Feature | Skeletal muscle | Visceral muscle | Cardiac muscle |
|---|---|---|---|
| Location | Attached to skeletal components | Walls of hollow visceral organs | Heart |
| Appearance | Striated | Smooth / non-striated | Striated and branching |
| Control | Voluntary | Involuntary | Involuntary; not directly controlled by nervous system |
| Main role | Locomotion and posture | Food movement through gut and gamete movement in genital tract | Heart contraction |
3. Sarcomere Regions and Filaments
| Structure | Composition / position | Significance |
|---|---|---|
| I band | Light isotropic band with thin actin; Z line bisects it | Shortens during contraction |
| A band | Dark anisotropic band with thick myosin; M line holds thick filaments centrally | Length remains constant during contraction |
| H zone | Central part of thick filament not overlapped by thin filament at rest | Reduces with contraction |
| Sarcomere | Region between successive Z lines | Functional unit of contraction |
| Myofilaments | Actin is thin and myosin is thick | Alternating arrangement creates striations |
4. Actin vs Myosin
| Feature | Actin | Myosin |
|---|---|---|
| Filament type | Thin | Thick |
| Basic organisation | Two helically wound F-actins, each polymerised from G-actin monomers | Polymerised from meromyosin monomers |
| Associated parts | Tropomyosin and regular troponin complex; resting troponin masks myosin-binding sites | Heavy meromyosin: head + short arm; light meromyosin: tail |
| Key functional feature | Ca2+-troponin interaction exposes active sites | Globular head is ATPase with ATP- and actin-binding sites; forms cross arm |
5. Resting vs Contracting Sarcomere
| Feature | Resting | Contracting |
|---|---|---|
| Ca2+ | Stored in sarcoplasmic reticulum; troponin masks actin sites | Released into sarcoplasm and binds troponin, exposing actin sites |
| Cross bridge | Myosin not attached to masked actin site | ATP-powered myosin head binds actin; repeated bridge cycles slide filaments |
| Z lines / sarcomere | Normal separation | Z lines move inwards; sarcomere shortens |
| I band and H zone | Relatively wider | Reduced |
| A band | Normal length | Unchanged length |
Relaxation Ca2+ is pumped back into sarcoplasmic cisternae, actin sites are masked again and cross bridges break when fresh ATP binds myosin.
6. Red vs White Muscle Fibres
| Feature | Red fibres | White fibres |
|---|---|---|
| Myoglobin / colour | High myoglobin; reddish | Very little myoglobin; pale or white |
| Mitochondria | Numerous | Few |
| Energy metabolism | Aerobic; uses large oxygen store for ATP production | Predominantly anaerobic |
| Sarcoplasmic reticulum | Not the defining abundant feature | High amount |
7. Axial vs Appendicular Skeleton; Girdles
| Feature | Axial skeleton | Appendicular skeleton |
|---|---|---|
| Composition | 80 bones: skull, vertebral column, sternum and ribs | Limb bones and pectoral/pelvic girdles |
| Important counts | Skull: 22; vertebral column: 26; ribs: 12 pairs | Each limb: 30 bones; hand/foot phalanges: 14 each |
| Major function | Main body axis, protection and support | Attachment and movement of limbs |
| Girdle detail | Not applicable | Pectoral half = clavicle + scapula; pelvic coxal = fused ilium, ischium and pubis. |
Ribs 1st-7th pairs are true; 8th-10th are false / vertebrochondral; 11th and 12th are floating. Femur is the longest bone; patella covers knee ventrally.
8. Fibrous vs Cartilaginous vs Synovial Joints
| Joint | Movement | Examples |
|---|---|---|
| Fibrous | None | Dense connective-tissue sutures between cranial bones |
| Cartilaginous | Limited | Between adjacent vertebrae |
| Synovial | Considerable; fluid-filled synovial cavity between articulating surfaces | Ball-and-socket shoulder, hinge knee, pivot atlas-axis, gliding carpals, saddle thumb joint |
Disorders Myasthenia gravis: autoimmune neuromuscular-junction disorder. Muscular dystrophy: progressive genetic skeletal-muscle degeneration. Tetany: low Ca2+ spasms. Arthritis: joint inflammation. Osteoporosis: low bone mass. Gout: uric-acid crystals in joints.